|Application ||WB, E|
|Calculated MW||27388 Da|
|Other Names||Cob(I)yrinic acid a, c-diamide adenosyltransferase, mitochondrial, Cob(I)alamin adenosyltransferase, Methylmalonic aciduria type B protein, MMAB|
|Target/Specificity||This MMAB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the Central region of human MMAB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MMAB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adenosyltransferase involved in intracellular vitamin B12 metabolism. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA.|
|Tissue Location||Expressed in liver and skeletal muscle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Dobson C.M.,et al.Hum. Mol. Genet. 11:3361-3369(2002).
Leal N.A.,et al.J. Biol. Chem. 278:9227-9234(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Schubert H.L.,et al.Biochemistry 45:15188-15196(2006).
Martinez M.A.,et al.Mol. Genet. Metab. 84:317-325(2005).
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