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KD-Validated Anti-MMAB Mouse Monoclonal Antibody

Mouse monoclonal Antibody

     
  • WB - KD-Validated Anti-MMAB Mouse Monoclonal Antibody AGI2160
    Western blotting analysis using anti-MMAB antibody (Cat#65033). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-MMAB antibody (Cat#65033, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
  • WB - KD-Validated Anti-MMAB Mouse Monoclonal Antibody AGI2160
    Western blotting analysis using anti-MMAB antibody (Cat#65033). MMAB expression in wild-type (WT) and MMAB knockdown (KD) HSHC cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-MMAB antibody (Cat#65033, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96EY8
Reactivity Human
Clonality Monoclonal
Isotype Mouse IgG2a
Clone Names 24GB13950
Calculated MW Predicted, 27 kDa, observed, 23 kDa
Gene Name MMAB
Aliases MMAB; Metabolism Of Cobalamin Associated B; CFAP23; CblB; Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type; ATP:Co(I)Rrinoid Adenosyltransferase MMAB; Cilia And Flagella Associated Protein 23; Methylmalonic Aciduria Type B Protein; ATP:Cob(I)Alamin Adenosyltransferase; Corrinoid Adenosyltransferase MMAB; Cob(I)Yrinic Acid A,C-Diamide Adenosyltransferase, Mitochondrial; Methylmalonic Aciduria (Cobalamin Deficiency) Type B; Cob(II)Yrinic Acid A,C-Diamide Adenosyltransferase; Aquocob(I)Alamin Vitamin B12s Adenosyltransferase; Cobinamide/Cobalamin Adenosyltransferase; ATP:Corrinoid Adenosyltransferase; Cob(II)Alamin Adenosyltransferase; Corrinoid Adenosyltransferase; EC 2.5.1.-; ATR; Cob
Immunogen Recombinant protein of human MMAB
Additional Information
Gene ID 326625
Other Names Corrinoid adenosyltransferase MMAB, 2.5.1.-, ATP:co(I)rrinoid adenosyltransferase MMAB, Methylmalonic aciduria type B protein, MMAB (HGNC:19331)
Protein Information
Name MMAB (HGNC:19331)
Function Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191). Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP- binding to MMAB and gated by MMAA (Probable).
Cellular Location Mitochondrion.
Tissue Location Expressed in liver and skeletal muscle.
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI2160
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