|Application ||WB, E|
|Calculated MW||47440 Da|
|Other Names||Brachyury protein, Protein T, T|
|Target/Specificity||This Mouse T antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 408-442 amino acids from the C-terminal region of human Mouse T.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse T Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation (PubMed:7588606). Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site (PubMed:8344258, PubMed:7588606).|
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Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Herrmann B.G.,et al.Nature 343:617-622(1990).
Kispert A.,et al.EMBO J. 12:3211-3220(1993).
Kispert A.,et al.EMBO J. 14:4763-4772(1995).
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