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Mouse T Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P20293 |
| Reactivity | Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47440 Da |
| Gene ID | 20997 |
|---|---|
| Other Names | Brachyury protein, Protein T, T |
| Target/Specificity | This Mouse T antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 408-442 amino acids from the C-terminal region of Mouse T. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse T Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Tbxt {ECO:0000250|UniProtKB:O15178} |
|---|---|
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation (PubMed:7588606). Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site (PubMed:7588606, PubMed:8344258). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
References
Herrmann B.G.,et al.Nature 343:617-622(1990).
Kispert A.,et al.EMBO J. 12:3211-3220(1993).
Kispert A.,et al.EMBO J. 14:4763-4772(1995).
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