ZDHHC14 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
 
| Application  
 | WB, E | 
|---|---|
| Primary Accession | Q8IZN3 | 
| Other Accession | Q8BQQ1 | 
| Reactivity | Mouse | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Isotype | Rabbit IgG | 
| Calculated MW | 53388 Da | 
| Antigen Region | 283-317 aa | 
| Gene ID | 79683 | 
|---|---|
| Other Names | Probable palmitoyltransferase ZDHHC14, NEW1 domain-containing protein, NEW1CP, Zinc finger DHHC domain-containing protein 14, DHHC-14, ZDHHC14 | 
| Target/Specificity | This ZDHHC14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 283-317 amino acids from the Central region of human ZDHHC14. | 
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. | 
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | 
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 
| Precautions | ZDHHC14 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | 
| Name | ZDHHC14 (HGNC:20341) | 
|---|---|
| Function | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and thereby regulate G protein-coupled receptor signaling (PubMed:27481942). May play a role in cell differentiation and apoptosis (PubMed:21151021, PubMed:24407904). | 
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein | 
| Tissue Location | Widely expressed.. | 

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Provided below are standard protocols that you may find useful for product applications.
References
Guo J.H.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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