SV2C Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q496J9 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 82342 Da |
| Antigen Region | 547-580 aa |
| Gene ID | 22987 |
|---|---|
| Other Names | Synaptic vesicle glycoprotein 2C, SV2C, KIAA1054 |
| Target/Specificity | This SV2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 547-580 amino acids from the C-terminal region of human SV2C. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SV2C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SV2C |
|---|---|
| Synonyms | KIAA1054 |
| Function | Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9Z2I6}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Z2I6}. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas {ECO:0000250|UniProtKB:Q9Z2I6} |

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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
References
Kikuno R.,et al.DNA Res. 6:197-205(1999).
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