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(Mouse) Gnl3 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - (Mouse) Gnl3 Antibody (C-term) AP21045a
    Western blot analysis of lysate from mouse liver tissue lysate, using Gnl3 Antibody (C-term)(Cat. #AP21045a). AP21045a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8CI11
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 60786 Da
Additional Information
Gene ID 30877
Other Names Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns
Target/Specificity This Mouse Gnl3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 450-483 amino acids from the C-terminal region of mouse Gnl3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(Mouse) Gnl3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Gnl3
Synonyms Ns
Function May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Cellular Location Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}
Tissue Location Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells.
Research Areas
Citations (0)
citation

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Background

May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.

References

Tsai R.Y.L.,et al.Genes Dev. 16:2991-3003(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).
Meng L.,et al.Oncogene 30:1716-1726(2011).

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$ 182.50
$ 70.00
Cat# AP21045a
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