(DANRE) cisd2 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q7T326 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 15485 Da |
Gene ID | 393354 |
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Other Names | CDGSH iron-sulfur domain-containing protein 2, cisd2 |
Target/Specificity | This DANRE cisd2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 110-144 amino acids from the human region of DANRE cisd2. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | (DANRE) cisd2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | cisd2 |
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Function | Regulator of autophagy that contributes to antagonize becn1- mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
References
Song H.-D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
Howe K.,et al.Nature 496:498-503(2013).
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