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YY1AP1 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - YY1AP1 Antibody (N-Term) AP21458a
    All lanes : Anti-YY1AP1 Antibody (N-Term) at 1:2000 dilution Lane 1: SK-BR-3 whole cell lysates Lane 2: MDA-MB-231 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 88 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9H869
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 87944 Da
Additional Information
Gene ID 55249
Other Names YY1-associated protein 1, Hepatocellular carcinoma susceptibility protein, Hepatocellular carcinoma-associated protein 2, YY1AP1, HCCA2, YY1AP
Target/Specificity This YY1AP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from human YY1AP1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsYY1AP1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name YY1AP1 (HGNC:30935)
Function Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641). Enhances transcription activation by YY1 (PubMed:14744866). Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641).
Cellular Location Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus
Tissue Location Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
Research Areas
Citations (0)
citation

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Background

Enhances transcription activation by YY1. May play a role in cell cycle regulation.

References

Wang Z.-X.,et al.Br. J. Cancer Suppl. 85:1162-1167(2001).
Wang C.-Y.,et al.J. Biol. Chem. 279:17750-17755(2004).
Zeng J.Z.,et al.Oncogene 21:4932-4943(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 182.50
$ 70.00
Cat# AP21458a
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