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SLC26A4 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O43511 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 85723 Da |
| Gene ID | 5172 |
|---|---|
| Other Names | Pendrin, Sodium-independent chloride/iodide transporter, Solute carrier family 26 member 4, SLC26A4, PDS |
| Target/Specificity | This SLC26A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 553-587 amino acids from human SLC26A4. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC26A4 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC26A4 |
|---|---|
| Synonyms | PDS |
| Function | Sodium-independent transporter of chloride and iodide (PubMed:10192399, PubMed:12107249, PubMed:11932316, PubMed:16684826, PubMed:24051746). Mediates electroneutral chloride-bicarbonate, chloride-iodide and chloride-formate exchange with 1:1 stoichiometry (PubMed:10644529, PubMed:15155570, PubMed:35601831, PubMed:24051746). Mediates electroneutral iodide-bicarbonate exchange (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein |
| Tissue Location | Highly expressed in the kidney (at protein level) (PubMed:11274445). High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues (PubMed:9398842). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Sodium-independent transporter of chloride and iodide.
References
Everett L.A.,et al.Nat. Genet. 17:411-422(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scott D.A.,et al.Nat. Genet. 21:440-443(1999).
van Hauwe P.,et al.Hum. Mol. Genet. 7:1099-1104(1998).
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