SRGAP3 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O43295 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 124504 Da |
Gene ID | 9901 |
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Other Names | SLIT-ROBO Rho GTPase-activating protein 3, srGAP3, Mental disorder-associated GAP, Rho GTPase-activating protein 14, WAVE-associated Rac GTPase-activating protein, WRP, SRGAP3, ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2 |
Target/Specificity | This SRGAP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 956-989 amino acids from the C-terminal region of human SRGAP3. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SRGAP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SRGAP3 |
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Synonyms | ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRG |
Function | GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. |
Tissue Location | Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
References
Soderling S.H.,et al.Nat. Cell Biol. 4:970-975(2002).
Endris V.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:11754-11759(2002).
Ishikawa K.,et al.DNA Res. 4:307-313(1997).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Wong K.,et al.Cell 107:209-221(2001).
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