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Ihh Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q80XI9 |
| Other Accession | Q91612, P97812, Q14623, Q98862, Q98938 |
| Reactivity | Human, Mouse |
| Predicted | Chicken, Zebrafish, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49445 Da |
| Antigen Region | 169-200 aa |
| Gene ID | 16147 |
|---|---|
| Other Names | Indian hedgehog |
| Target/Specificity | This Ihh antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-200 amino acids from the C-terminal region of human Ihh. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Ihh Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Ihh {ECO:0000313|EMBL:AAH46984.1, ECO:0000313|MGI:MGI:96533} |
|---|---|
| Function | [Protein hedgehog N-product]: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Secreted {ECO:0000256|ARBA:ARBA00004613} [Protein hedgehog N-product]: Cell membrane {ECO:0000256|RuleBase:RU280812}; Lipid-anchor {ECO:0000256|RuleBase:RU280812} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Ihh (Indian hedgehog) is a critical and possibly direct regulator of joint development. In its absence, distribution and function of Gdf5-expressing interzone-associated cells are abnormal.
References
Kobayashi,T., Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1949-1954 (2008)
Gat-Yablonski,G.,J. Pediatr. Endocrinol. Metab. 20 (11), 1215-1222 (2007)
Koyama,E., Ann. N. Y. Acad. Sci. 1116, 100-112 (2007)
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