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WIF1 Antibody(Human C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P-Leica, WB, E |
|---|---|
| Primary Accession | Q9Y5W5 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41528 Da |
| Antigen Region | 347-376 aa |
| Gene ID | 11197 |
|---|---|
| Other Names | Wnt inhibitory factor 1, WIF-1, WIF1 |
| Target/Specificity | This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human WIF1. |
| Dilution | IHC-P-Leica~~1:500 WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WIF1 Antibody(Human C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | WIF1 |
|---|---|
| Function | Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. |
| Cellular Location | Secreted. |
Provided below are standard protocols that you may find useful for product applications.
Background
WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.
References
Elston,M.S., Endocrinology 149 (3), 1235-1242 (2008)
Clement,G., Cancer Sci. 99 (1), 46-53 (2008)
Chan,S.L., Lab. Invest. 87 (7), 644-650 (2007)
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