Phospho-JMJD1B(S291) Antibody
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| DB, E |
|---|---|
| Primary Accession | Q7LBC6 |
| Other Accession | NP_057688.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 191581 Da |
| Gene ID | 51780 |
|---|---|
| Other Names | Lysine-specific demethylase 3B, 11411-, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082 |
| Target/Specificity | This JMJD1B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S291 of human JMJD1B. |
| Dilution | DB~~1:500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Phospho-JMJD1B(S291) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KDM3B |
|---|---|
| Synonyms | C5orf7, JHDM2B, JMJD1B, KIAA1082 |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. |

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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Yamane, K., et al. Cell 125(3):483-495(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
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