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PAR6G Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BYG4 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40883 Da |
| Antigen Region | 18-47 aa |
| Gene ID | 84552 |
|---|---|
| Other Names | Partitioning defective 6 homolog gamma, PAR-6 gamma, PAR6D, PARD6G, PAR6G |
| Target/Specificity | This PAR6G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human PAR6G. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PAR6G Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PARD6G |
|---|---|
| Synonyms | PAR6G |
| Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity). |
| Cellular Location | Cytoplasm. Cell membrane. Cell junction, tight junction |
| Tissue Location | Widely expressed, with a higher expression in fetal and adult kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
PAR6G involved in asymmetrical cell division and cell polarization processes. PAR6G may play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
References
Brajenovic, M., et al. J. Biol. Chem. 279(13):12804-12811(2004)
Kohjima, M., et al. Biochem. Biophys. Res. Commun. 299(4):641-646(2002)
Suzuki, A., et al. J. Cell Biol. 152(6):1183-1196(2001)
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