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CWC15 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9P013 |
| Other Accession | Q5BJP2, Q9JHS9, Q2KJD3 |
| Reactivity | Human, Hamster |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26624 Da |
| Antigen Region | 123-152 aa |
| Gene ID | 51503 |
|---|---|
| Other Names | Spliceosome-associated protein CWC15 homolog, CWC15, C11orf5 |
| Target/Specificity | This CWC15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-152 amino acids from the Central region of human CWC15. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CWC15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CWC15 |
|---|---|
| Synonyms | C11orf5 |
| Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28076346, PubMed:28502770). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
CWC15 involved in pre-mRNA splicing.
References
Anney, R.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1369-1378 (2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Ohi, M.D., et al. Mol. Cell. Biol. 22(7):2011-2024(2002)
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