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TCTP Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P13693 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 20,16 KDa |
| Antigen Region | 85-115 aa |
| Gene ID | 7178 |
|---|---|
| Other Names | Translationally-controlled tumor protein, TCTP, Fortilin, Histamine-releasing factor, HRF, p23, TPT1 |
| Dilution | WB~~ 1:1000 IHC~~1:50-1:100 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | TPT1 |
|---|---|
| Function | Involved in calcium binding and microtubule stabilization (PubMed:12167714, PubMed:15162379, PubMed:15958728). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (PubMed:18325344). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in calcium binding and microtubule stabilization.
References
Gross B.,et al.Nucleic Acids Res. 17:8367-8367(1989).
Thiele H.,et al.Thesis (2000), Humboldt-University Berlin, Germany.
Gnanasekar M.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Gao T.H.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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