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KRT82 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NSB4 |
| Other Accession | Q99M74 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 56653 Da |
| Antigen Region | 312-341 aa |
| Gene ID | 3888 |
|---|---|
| Other Names | Keratin, type II cuticular Hb2, Keratin-82, K82, Type II hair keratin Hb2, Type-II keratin Kb22, KRT82, KRTHB2 |
| Target/Specificity | This KRT82 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the Central region of human KRT82. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KRT82 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT82 |
|---|---|
| Synonyms | KRTHB2 |
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Provided below are standard protocols that you may find useful for product applications.
Background
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006) Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)
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