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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > Anti-JAZF1 antibody
Anti-JAZF1 antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q86VZ6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Calculated MW | H=27 KDa |
| Antigen Region | 31-130/243 human aa |
| Gene ID | 221895 |
|---|---|
| Other Names | Juxtaposed with another zinc finger protein 1, TAK1-interacting protein 27, Zinc finger protein 802, JAZF1, TIP27, ZNF802 |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | JAZF1 (HGNC:28917) |
|---|---|
| Synonyms | TIP27, ZNF802 |
| Function | Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (PubMed:15302918). Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Potential transcription factor.
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Discontinued
Cat# AP50814
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