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CCDC62 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q6P9F0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 77748 Da |
| Antigen Region | 651-679 aa |
| Gene ID | 84660 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 62, Protein TSP-NY, Protein aaa, CCDC62 |
| Target/Specificity | This CCDC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 amino acids from the C-terminal region of human CCDC62. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCDC62 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCDC62 |
|---|---|
| Function | Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. Required for normal spermiogenesis. It probably plays a role in acrosome formation (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly nuclear |
| Tissue Location | Highly expressed in adult testis. Expressed in both prostate epithelial and stromal cells, with predominant expression in epithelial cells (at protein level) (PubMed:19126643). Not detected in prostate by RT-PCR (PubMed:19165854). Overexpressed in various cancers {ECO:0000269|PubMed:19126643, ECO:0000269|PubMed:19165854, ECO:0000269|Ref.1, ECO:0000269|Ref.4} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein has not been specifically defined.
References
Domae, S., et al. Int. J. Cancer 124(10):2347-2352(2009)
Chen, M., et al. Carcinogenesis 30(5):841-850(2009)
Chen, M., et al. Prostate 68(12):1273-1282(2008)
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