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CD300LB Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A8K4G0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22689 Da |
| Antigen Region | 57-85 aa |
| Gene ID | 124599 |
|---|---|
| Other Names | CMRF35-like molecule 7, CLM-7, CD300 antigen-like family member B, CMRF35-A2, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5, Triggering receptor expressed on myeloid cells 5, TREM-5, CD300b, CD300LB, CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TREM5 |
| Target/Specificity | This CD300LB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD300LB. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CD300LB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CD300LB |
|---|---|
| Synonyms | CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TR |
| Function | Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed exclusively in myeloid lineages. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006.
References
Yamanishi, Y., et al. Blood 111(2):688-698(2008)
Martinez-Barriocanal, A., et al. J. Immunol. 177(5):2819-2830(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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