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SMYD1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8NB12 |
| Reactivity | Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Calculated MW | 56 KDa |
| Gene ID | 150572 |
|---|---|
| Other Names | BOP;CD8 beta opposite;CD8b opposite;Histone lysine N methyltransferase SMYD1;KMT3D;SET and MYND domain-containing protein 1;SMYD1;SMYD1_HUMAN;Zinc finger MYND domain containing 18;ZMYND18;ZMYND22;zinc finger, MYND domain containing 18. |
| Dilution | WB~~1:100 |
| Format | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.09% (W/V) sodium azide, 50% glycerol |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SMYD1 |
|---|---|
| Function | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
| Cellular Location | Cytoplasm. Nucleus. |
| Tissue Location | Expression seems mostly restricted to heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li D.,et al.Nucleic Acids Res. 37:7059-7071(2009).
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