Mannose Phosphate Isomerase Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | P34949 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 54 KDa |
Gene ID | 4351 |
---|---|
Other Names | PMI1;CDG1B;FLJ39201;Mannose 6 phosphate isomerase;Mannose-6-phosphate isomerase; MANNOSEPHOSPHATE ISOMERASE;MGC94106;MPI;MPI_HUMAN;Phosphohexomutase;phosphomannose isomerase 1;Phosphomannose isomerase;PMI;PMI1. |
Dilution | WB~~1:1000 ICC~~1:300 |
Format | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.09% (W/V) sodium azide, 50%,glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MPI (HGNC:7216) |
---|---|
Synonyms | PMI1 |
Function | Isomerase that catalyzes the interconversion of fructose-6-P and mannose-6-P and has a critical role in the supply of D-mannose derivatives required for many eukaryotic glycosylation reactions. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q924M7}. |
Tissue Location | Expressed in all tissues, but more abundant in heart, brain and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
References
Proudfoot A.E.I.,et al.Eur. J. Biochem. 219:415-423(1994).
Schollen E.,et al.Hum. Mutat. 16:247-252(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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