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UTP6 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q9NYH9 |
| Other Accession | Q8VCY6 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70194 Da |
| Antigen Region | 16-43 aa |
| Gene ID | 55813 |
|---|---|
| Other Names | U3 small nucleolar RNA-associated protein 6 homolog, Hepatocellular carcinoma-associated antigen 66, Multiple hat domains protein, UTP6, C17orf40, HCA66, MHAT |
| Target/Specificity | This UTP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human UTP6. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UTP6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UTP6 (HGNC:18279) |
|---|---|
| Synonyms | C17orf40, HCA66, MHAT |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. |
| Cellular Location | Nucleus, nucleolus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
UTP6 involved in nucleolar processing of pre-18S ribosomal RNA.
References
Fant, X., et al. J. Cell. Sci. 122 (PT 8), 1134-1144 (2009)
Douglas, J., et al. Nat. Genet. 39(8):963-965(2007)
Piddubnyak, V., et al. Cell Death Differ. 14(6):1222-1233(2007)
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