MVK Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q03426 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42 KDa |
Antigen Region | 153-202 aa |
Gene ID | 4598 |
---|---|
Dilution | WB~~ 1:1000 |
Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MVK (HGNC:7530) |
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Function | Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed:11278915, PubMed:18302342, PubMed:9325256, PubMed:9392419). |
Cellular Location | Cytoplasm. Peroxisome {ECO:0000250|UniProtKB:P17256} |

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Provided below are standard protocols that you may find useful for product applications.
Background
May be a regulatory site in cholesterol biosynthetic pathway.
References
Schafer B.L.,et al.J. Biol. Chem. 267:13229-13238(1992).
Graef E.,et al.Oncogene 9:81-87(1994).
Houten S.M.,et al.Eur. J. Hum. Genet. 9:253-259(2001).
Houten S.M.,et al.Eur. J. Hum. Genet. 9:651-651(2001).
Hogenboom S.,et al.J. Cell Sci. 117:631-639(2004).

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