Anti-Histone H1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, IHC |
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Primary Accession | P16401 |
Other Accession | P16402, P10412 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22580 Da |
Gene ID | 3009 |
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Other Names | HIST1H1B; H1F5; Histone H1.5; Histone H1a; Histone H1b; Histone H1s-3; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4 |
Target/Specificity | Recognizes endogenous levels of Histone H1 protein. |
Dilution | WB~~1/500 - 1/1000 IH~~1/50 - 1/200 IF~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | H1-5 (HGNC:4719) |
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Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
Cellular Location | Nucleus. Chromosome. Note=Mainly localizes with heterochromatin (PubMed:15911621). Associates with actively transcribed chromatin and not heterochromatin (PubMed:10997781) |
Tissue Location | Ubiquitous. Expressed in the majority of the cell lines tested and in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to Histone H1
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