Anti-PDE4B/C/D Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q07343 |
Other Accession | Q08493, Q08499 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 83343 Da |
Gene ID | 5142 |
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Other Names | PDE4B; DPDE4; cAMP-specific 3', 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3', 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3', 5'-cyclic phosphodiesterase 4D; DPDE3; PDE43 |
Target/Specificity | Recognizes endogenous levels of PDE4B/C/D protein. |
Dilution | WB~~1/500 - 1/1000 IH~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | PDE4B (HGNC:8781) |
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Synonyms | DPDE4 |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:15260978). May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
Cellular Location | [Isoform PDE4B5]: Cytoplasm. Cell membrane |
Tissue Location | Expressed in brain, heart, lung and skeletal muscle (PubMed:17519386). Expressed in white blood cells (PubMed:8392015) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to PDE4B/C/D
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