C14orf179 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q96FT9 |
Other Accession | Q9DA69, Q2TBN9, NP_001096034.1, NP_443105.2 |
Reactivity | Human, Mouse |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 23529 Da |
Antigen Region | 145-171 aa |
Gene ID | 112752 |
---|---|
Other Names | Intraflagellar transport protein 43 homolog, IFT43, C14orf179 |
Target/Specificity | This C14orf179 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human C14orf179. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | C14orf179 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IFT43 (HGNC:29669) |
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Synonyms | C14orf179 |
Function | As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis (PubMed:28400947, PubMed:28973684). Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (PubMed:21378380). |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium Note=Associated with microtubules (PubMed:22361696). Localized at the distal tip of the cilium (PubMed:28973684) |
Tissue Location | Expressed in the retina, predominantly in the photoreceptor outer segment. |
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Provided below are standard protocols that you may find useful for product applications.
References
Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :
Heilig, R., et al. Nature 421(6923):601-607(2003)
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