IFT43 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
 
| Application  
 | WB, IHC-P, FC, E | 
|---|---|
| Primary Accession | Q96FT9 | 
| Other Accession | Q9DA69, Q2TBN9, NP_001096034.1, NP_443105.2 | 
| Reactivity | Human, Mouse | 
| Predicted | Bovine | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Isotype | Rabbit IgG | 
| Calculated MW | 23529 Da | 
| Antigen Region | 145-171 aa | 
| Gene ID | 112752 | 
|---|---|
| Other Names | Intraflagellar transport protein 43 homolog, IFT43, C14orf179 | 
| Target/Specificity | This C14orf179 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human C14orf179. | 
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 E~~Use at an assay dependent concentration. | 
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | 
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 
| Precautions | IFT43 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | 
| Name | IFT43 (HGNC:29669) | 
|---|---|
| Synonyms | C14orf179 | 
| Function | As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis (PubMed:28400947, PubMed:28973684). Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (PubMed:21378380). | 
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium Note=Associated with microtubules (PubMed:22361696). Localized at the distal tip of the cilium (PubMed:28973684) | 
| Tissue Location | Expressed in the retina, predominantly in the photoreceptor outer segment. | 

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :
Heilig, R., et al. Nature 421(6923):601-607(2003)

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