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Anti-NCKX1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | O60721 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 121374 Da |
| Gene ID | 9187 |
|---|---|
| Other Names | KIAA0702; NCKX1; Sodium/potassium/calcium exchanger 1; Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1 |
| Target/Specificity | Recognizes endogenous levels of NCKX1 protein. |
| Dilution | WB~~1/500 - 1/1000 IF~~1/50 - 1/200 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SLC24A1 {ECO:0000303|PubMed:20850105, ECO:0000312|HGNC:HGNC:10975} |
|---|---|
| Function | Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:26631410). Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness (PubMed:20850105). Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation (PubMed:20850105). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to NCKX1
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$ 385.00
Cat# AP53719
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