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Anti-A-MYB Antibody

     
  • WB - Anti-A-MYB Antibody AP53778
    Western blot analysis of A-MYB expression in mouse brain (A), rat brain (B) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P10243
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 85887 Da
Additional Information
Gene ID 4603
Other Names AMYB; Myb-related protein A; A-Myb; Myb-like protein 1
Target/Specificity Recognizes endogenous levels of A-MYB protein.
Dilution WB~~1/500 - 1/1000
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MYBL1
Synonyms AMYB
Function Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity). Transcriptional activator of SOX30 (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P51960}.
Tissue Location Expressed in a variety of lymphoid and solid tumor lines cultured in vitro
Research Areas
Citations (0)
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Background

Rabbit polyclonal antibody to A-MYB

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$ 350.00
Cat# AP53778
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