Anti-SP3/4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF |
---|---|
Primary Accession | Q02447 |
Other Accession | Q02446 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 81925 Da |
Gene ID | 6670 |
---|---|
Other Names | SP3; Transcription factor Sp3; SPR-2; SP4; Transcription factor Sp4; SPR-1 |
Target/Specificity | Recognizes endogenous levels of SP3/4 protein. |
Dilution | WB~~1/500 - 1/1000 IF~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | SP3 |
---|---|
Function | Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping. |
Cellular Location | Nucleus. Nucleus, PML body. Note=Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies |
Tissue Location | Ubiquitously expressed. |

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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to SP3/4

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