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Anti-PINX1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q96BK5 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37035 Da |
| Gene ID | 54984 |
|---|---|
| Other Names | LPTL; LPTS; PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1 |
| Target/Specificity | Recognizes endogenous levels of PINX1 protein. |
| Dilution | WB~~1/500 - 1/1000 IH~~1/50 - 1/200 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | PINX1 |
|---|---|
| Synonyms | LPTL, LPTS |
| Function | Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. |
| Cellular Location | Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE |
| Tissue Location | Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to PINX1
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$ 350.00
Cat# AP53860
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