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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-5-HT7 Antibody
Anti-5-HT7 Antibody
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P34969 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53555 Da |
| Gene ID | 3363 |
|---|---|
| Other Names | 5-hydroxytryptamine receptor 7; 5-HT-7; 5-HT7; 5-HT-X; Serotonin receptor 7 |
| Target/Specificity | Recognizes endogenous levels of 5-HT7 protein. |
| Dilution | WB~~1/500 - 1/1000 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | HTR7 {ECO:0000303|Ref.3, ECO:0000312|HGNC:HGNC:5302} |
|---|---|
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:8226867). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (PubMed:35714614, PubMed:8226867). HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (PubMed:35714614). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | [Isoform A]: Predominant isoform in spleen, caudate and hippocampus. [Isoform D]: Minor isoform in terms of expression. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to 5-HT7
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$ 385.00
Cat# AP53890
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