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Anti-MCT12 Antibody

     
  • WB - Anti-MCT12 Antibody AP53919
    Western blot analysis of MCT12 expression in Jurkat (A) whole cell lysates.
    detail
  • IH - Anti-MCT12 Antibody AP53919
    Immunohistochemical analysis of MCT12 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q6ZSM3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 56498 Da
Additional Information
Gene ID 387700
Other Names MCT12; Monocarboxylate transporter 12; MCT 12; Solute carrier family 16 member 12
Target/Specificity Recognizes endogenous levels of MCT12 protein.
Dilution WB~~1/500 - 1/1000
IH~~1/50 - 1/200
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name SLC16A12 (HGNC:23094)
Function Functions as a transporter for creatine and as well for its precursor guanidinoacetate. Transport of creatine and GAA is independent of resting membrane potential and extracellular Na(+), Cl(-), or pH. Contributes to the process of creatine biosynthesis and distribution.
Cellular Location Cell membrane; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8BGC3}; Multi-pass membrane protein. Note=Interaction with isoform 2 of BSG is required for its localization to the plasma membrane.
Tissue Location Most highly expressed in kidney, followed by retina, lung, heart and testis. Very weakly expressed in brain and liver. Also detected in lens.
Research Areas
Citations (0)
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Background

Rabbit polyclonal antibody to MCT12

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$ 350.00
Cat# AP53919
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