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Anti-RRP7A/B Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9Y3A4 |
| Other Accession | Q9NSQ0 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 32334 Da |
| Gene ID | 27341 |
|---|---|
| Other Names | RRP7A; CGI-96; Ribosomal RNA-processing protein 7 homolog A; Gastric cancer antigen Zg14; RRP7B; Putative ribosomal RNA-processing protein 7 homolog B; Putative gastric cancer antigen Zg14-like protein |
| Target/Specificity | Recognizes endogenous levels of RRP7A/B protein. |
| Dilution | WB~~1/500 - 1/2000 IH~~1/50 - 1/200 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | RRP7A (HGNC:24286) |
|---|---|
| Function | Nucleolar protein that is involved in ribosomal RNA (rRNA) processing (PubMed:33199730). Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development (PubMed:33199730). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). |
| Cellular Location | Nucleus, nucleolus. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
| Tissue Location | Expressed in the apical radial glial cells in the developing brain. |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to RRP7A/B
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$ 350.00
Cat# AP53942
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