ACY3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, E |
---|---|
Primary Accession | Q96HD9 |
Reactivity | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human ACY 3 |
Epitope Specificity | 221-319/319 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Apical cell membrane; Peripheral membrane protein. Cytoplasm. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm. |
SIMILARITY | Belongs to the AspA/AstE family. Aspartoacylase subfamily. |
SUBUNIT | Homotetramer. Interacts with HCV core protein. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | ACY3 belongs to the aspA/astE family. Aspartoacylase subfamily. Catalytic activity: N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate. Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. |
Gene ID | 91703 |
---|---|
Other Names | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), 3.5.1.114, Acylase III, Aminoacylase-3, ACY-3, Aspartoacylase-2, Hepatitis C virus core-binding protein 1, HCBP1, HCV core-binding protein 1, ACY3, ASPA2 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | ACY3 |
---|---|
Synonyms | ASPA2 |
Function | Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). |
Cellular Location | Apical cell membrane; Peripheral membrane protein. Cytoplasm Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm |

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