ACY3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q96HD9 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ACY 3 |
| Epitope Specificity | 221-319/319 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Apical cell membrane; Peripheral membrane protein. Cytoplasm. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm. |
| SIMILARITY | Belongs to the AspA/AstE family. Aspartoacylase subfamily. |
| SUBUNIT | Homotetramer. Interacts with HCV core protein. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | ACY3 belongs to the aspA/astE family. Aspartoacylase subfamily. Catalytic activity: N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate. Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. |
| Gene ID | 91703 |
|---|---|
| Other Names | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), 3.5.1.114, Acylase III, Aminoacylase-3, ACY-3, Aspartoacylase-2, Hepatitis C virus core-binding protein 1, HCBP1, HCV core-binding protein 1, ACY3, ASPA2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | ACY3 |
|---|---|
| Synonyms | ASPA2 |
| Function | Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). |
| Cellular Location | Apical cell membrane; Peripheral membrane protein. Cytoplasm Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm |

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