|Application ||FC, WB, E|
|Calculated MW||35241 Da|
|Antigen Region||66-95 aa|
|Other Names||N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, ACY-3, Aspartoacylase-2, Hepatitis C virus core-binding protein 1, HCBP1, HCV core-binding protein 1, ACY3, ASPA2|
|Target/Specificity||This ACY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the Central region of human ACY3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACY3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity).|
|Cellular Location||Apical cell membrane; Peripheral membrane protein. Cytoplasm Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ACY3 belongs to the aspA/astE family. Aspartoacylase subfamily. Catalytic activity: N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate
Chen,Y.R., et.al., J. Gastroenterol. Hepatol. 24 (7), 1300-1304 (2009)
Pushkin,A., et.al., Am. J. Physiol., Cell Physiol. 286 (4), C848-C856 (2004)
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