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Myosin-3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | P11055 |
| Reactivity | Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 224 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Myosin-3 |
| Epitope Specificity | 1801-1940/1940 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. |
| SIMILARITY | Contains 1 IQ domain.Contains 1 myosin head-like domain. |
| SUBUNIT | Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). |
| DISEASE | Arthrogryposis, distal, 2A (DA2A) [MIM:193700]: A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2A is characterized by contractures of the hands and feet, oropharyngeal abnormalities, scoliosis, and a distinctive face that includes a very small oral orifice, puckered lips, and an H-shaped dimple of the chin. Note=The disease is caused by mutations affecting the gene represented in this entry.Arthrogryposis, distal, 2B (DA2B) [MIM:601680]: A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 4621 |
|---|---|
| Other Names | Myosin-3, Muscle embryonic myosin heavy chain, Myosin heavy chain 3, Myosin heavy chain, fast skeletal muscle, embryonic, SMHCE, MYH3 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | MYH3 |
|---|---|
| Function | Muscle contraction. |
| Cellular Location | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils |
| Tissue Location | Expressed in fetal bone, thymus, placenta, heart, brain, and liver. |
Research Areas
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP54317
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