CCBL1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q16773 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 47875 Da |
Gene ID | 883 |
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Other Names | Kynurenine--oxoglutarate transaminase 1, 2.6.1.7, Cysteine-S-conjugate beta-lyase, 4.4.1.13, Glutamine transaminase K, GTK, Glutamine--phenylpyruvate transaminase, 2.6.1.64, Kynurenine aminotransferase 1 {ECO:0000312|HGNC:HGNC:1564}, Kynurenine aminotransferase I, KATI, Kynurenine--oxoglutarate transaminase I, KYAT1 (HGNC:1564), CCBL1 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | KYAT1 (HGNC:1564) |
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Synonyms | CCBL1 |
Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others (PubMed:19338303, PubMed:28097769). Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites (PubMed:7883047). Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047). |
Cellular Location | Cytoplasm, cytosol. |
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