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LSP1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | P33241 |
| Other Accession | NP_002330 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37192 Da |
| Antigen Region | 108-134 aa |
| Gene ID | 4046 |
|---|---|
| Other Names | Lymphocyte-specific protein 1, 47 kDa actin-binding protein, 52 kDa phosphoprotein, pp52, Lymphocyte-specific antigen WP34, LSP1, WP34 |
| Target/Specificity | This LSP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-134 amino acids from the Central region of human LSP1. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:8000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LSP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LSP1 |
|---|---|
| Synonyms | WP34 |
| Function | May play a role in mediating neutrophil activation and chemotaxis. |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side |
| Tissue Location | Activated T-lymphocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
LSP1 is an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
References
Davila, S., et al. Genes Immun. (2010)
Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010)
Bhatti, P., et al. Radiat. Res. 173(2):214-224(2010)
Tamimi, R.M., et al. Cancer Causes Control (2010)
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