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HBLD2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q9BUE6 |
| Reactivity | Rat, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 13 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human HBLD2 |
| Epitope Specificity | 1-100/129 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Mitochondrion. |
| SIMILARITY | Belongs to the HesB/IscA family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]). |
| Gene ID | 81689 |
|---|---|
| Other Names | Iron-sulfur cluster assembly 1 homolog, mitochondrial, HESB-like domain-containing protein 2, Iron-sulfur assembly protein IscA, hIscA, ISCA1, HBLD2 |
| Target/Specificity | Detected in cerebellum, kidney and heart. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | ISCA1 |
|---|---|
| Synonyms | HBLD2 |
| Function | Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. |
| Cellular Location | Mitochondrion |
| Tissue Location | Detected in cerebellum, kidney and heart. |
Research Areas
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Application Protocols
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$ 385.00
Cat# AP55984
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