HBLD2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HBLD2.
|Application ||WB, E|
|Calculated MW||14179 Da|
|Other Names||Iron-sulfur cluster assembly 1 homolog, mitochondrial, HESB-like domain-containing protein 2, Iron-sulfur assembly protein IscA, hIscA, ISCA1, HBLD2|
|Target/Specificity||HBLD2 (AAH02675, 1 a.a. ~ 129 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HBLD2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]).
Iron-binding activity of human iron-sulfur cluster assembly protein hIscA1. Lu J, et al. Biochem J, 2010 Apr 28. PMID 20302570.Human ISCA1 interacts with IOP1/NARFL and functions in both cytosolic and mitochondrial iron-sulfur protein biogenesis. Song D, et al. J Biol Chem, 2009 Dec 18. PMID 19864422.Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. Nilsson R, et al. Cell Metab, 2009 Aug. PMID 19656490.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.hIscA: a protein implicated in the biogenesis of iron-sulfur clusters. C?zar-Castellano I, et al. Biochim Biophys Acta, 2004 Aug 2. PMID 15262227.
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