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CTNNAL1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9UBT7 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 81 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human CTNNAL1 |
| Epitope Specificity | 151-250/743 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. |
| SIMILARITY | Belongs to the vinculin/alpha-catenin family. |
| SUBUNIT | Interacts with ARHGEF1. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms. |
| Gene ID | 8727 |
|---|---|
| Other Names | Alpha-catulin, Alpha-catenin-related protein, ACRP, Catenin alpha-like protein 1, CTNNAL1 |
| Target/Specificity | Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | CTNNAL1 |
|---|---|
| Function | May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein |
| Tissue Location | Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP56441
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