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LARP4B/LARP5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, ICC |
|---|---|
| Primary Accession | Q92615 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 81 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LARP4B/LARP5 |
| Epitope Specificity | 401-500/738 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm, cytosol |
| SIMILARITY | Contains 1 HTH La-type RNA-binding domain. Contains 1 RRM (RNA recognition motif) domain. |
| SUBUNIT | Interacts with PABPC1 and GNB2L1. Associates with polysomes via the 40S ribosomal subunit. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012] |
| Gene ID | 23185 |
|---|---|
| Other Names | La-related protein 4B, La ribonucleoprotein domain family member 4B, La ribonucleoprotein domain family member 5, La-related protein 5, LARP4B, KIAA0217, LARP5 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | LARP4B |
|---|---|
| Synonyms | KIAA0217, LARP5 |
| Function | Stimulates mRNA translation. |
| Cellular Location | Cytoplasm, cytosol. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs in response to arsenite treatment. |
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP56560
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