MONDOA Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9HAP2 |
Reactivity | Rat, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 101185 Da |
Gene ID | 22877 |
---|---|
Other Names | MLX-interacting protein, Class E basic helix-loop-helix protein 36, bHLHe36, Transcriptional activator MondoA, MLXIP (HGNC:17055) |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MLXIP (HGNC:17055) |
---|---|
Function | Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
Cellular Location | Cytoplasm. Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Mitochondrion outer membrane Note=Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. {ECO:0000250|UniProtKB:Q2VPU4, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875} |
Tissue Location | Widely expressed in adult tissues. Most abundant in skeletal muscle. |
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