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NLRC5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q86WI3 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 204 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human NLRC5 |
| Epitope Specificity | 651-750/1866 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the NLRP family. Contains 26 LRR (leucine-rich) repeats. Contains 1 NACHT domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011] |
| Gene ID | 84166 |
|---|---|
| Other Names | Protein NLRC5, Caterpiller protein 16.1, CLR16.1, Nucleotide-binding oligomerization domain protein 27, Nucleotide-binding oligomerization domain protein 4, NLRC5, NOD27, NOD4 |
| Target/Specificity | Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | NLRC5 |
|---|---|
| Synonyms | NOD27, NOD4 |
| Function | Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. |
| Cellular Location | Cytoplasm |
| Tissue Location | Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. |
Research Areas
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Application Protocols
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$ 385.00
Cat# AP57462
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