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RALGPS2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC |
|---|---|
| Primary Accession | Q86X27 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human RALGPS2 |
| Epitope Specificity | 481-583/583 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain. |
| SUBUNIT | Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA. |
| DISEASE | RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain. |
| Gene ID | 55103 |
|---|---|
| Other Names | Ras-specific guanine nucleotide-releasing factor RalGPS2, Ral GEF with PH domain and SH3-binding motif 2, RalA exchange factor RalGPS2, RALGPS2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | RALGPS2 |
|---|---|
| Function | Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). |
| Cellular Location | Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain |
Research Areas
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP57915
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