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SLC44A1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q8WWI5 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 73 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SLC44A1/CD92 |
| Epitope Specificity | 81-180/657 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the CTL (choline transporter-like) family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | SLC44A1 (Solute carrier family 44, member 1) is an intermediate-affinity, Na+-independent choline transporter. It is thought to be important for the production of the membrane lipid phosphatidylcholine. Hence, it may have a role in membrane synthesis and myelin production. |
| Gene ID | 23446 |
|---|---|
| Other Names | Choline transporter-like protein 1, CDw92, Solute carrier family 44 member 1, CD92, SLC44A1, CD92, CDW92, CTL1 |
| Target/Specificity | Expressed in various cells of the hematopoietic system. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SLC44A1 (HGNC:18798) |
|---|---|
| Synonyms | CD92, CDW92, CTL1 |
| Function | Choline/H+ antiporter (PubMed:19357133, PubMed:23651124, PubMed:31855247, PubMed:33789160). Also acts as a high-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway (PubMed:33789160). Involved in membrane synthesis and myelin production (PubMed:31855247). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in various cells of the hematopoietic system. |
Research Areas
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP58088
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