LZTFL1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9NQ48 |
| Reactivity | Rat, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LZTFL1 |
| Epitope Specificity | 101-200/299 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the LZTFL 1 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | LZTFL1 (Leucine zipper transcription factor-like 1) contains a leucine zipper pattern and coiled-coil domains. |
| Gene ID | 54585 |
|---|---|
| Other Names | Leucine zipper transcription factor-like protein 1, LZTFL1 |
| Target/Specificity | Expressed in testis, heart, skeletalmuscle, pancreas,t hymus, spleen, prostate, ovary, smallintestine, colon, and peripheral blood leukocytes. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | LZTFL1 |
|---|---|
| Function | Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. |
| Cellular Location | Cytoplasm |
| Tissue Location | Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes |

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