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TRIM47 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q96LD4 |
| Reactivity | Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 70 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human TRIM47 |
| Epitope Specificity | 414-460/638 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm. Nucleus. |
| SIMILARITY | Belongs to the TRIM/RBCC family.Contains 1 B box-type zinc finger.Contains 1 B30.2/SPRY domain.Contains 1 RING-type zinc finger. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | TRIM47 belongs to the TRIM/RBCC family. It contains one B box type zinc finger, one B30.2/SPRY domain and one RING type zinc finger. TRIM47 has low expression in most tissues; higher expression in kidney tubular cells and over expressed in astrocytoma tumor cells. |
| Gene ID | 91107 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase TRIM47, 2.3.2.27, Gene overexpressed in astrocytoma protein, RING finger protein 100, Tripartite motif-containing protein 47, TRIM47 (HGNC:19020), GOA, RNF100 |
| Target/Specificity | Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | TRIM47 (HGNC:19020) |
|---|---|
| Synonyms | GOA, RNF100 |
| Function | E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD. |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP58501
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